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. Author manuscript; available in PMC: 2020 Dec 21.
Published in final edited form as: J Psychopharmacol. 2018 Jun 27;32(7):770–778. doi: 10.1177/0269881118780713

Table 2.

Summary of results by dose.

Dose 1 (n=12) Dose 2 (n=11) Dose 3 (n=10) F(2, 19) p-Value
MEQ subscales
Mystical (unity, noetic, sacred) 0.53 (0.37–0.69) 0.60 (0.44–0.76) 0.65 (0.48–0.82) 1.10 0.354
Positive mood 0.68 (0.56–0.80) 0.64 (0.51–0.77) 0.72 (0.58–0.85) 0.60 0.56
Transcendence of time and space 0.54 (0.40–0.68) 0.65 (0.51–0.79) 0.73 (0.58–0.88) 5.73 0.011
Ineffability 0.73 (0.62–0.85) 0.78 (0.66–0.90) 0.81 (0.69–0.94) 0.38 0.38
MEQ total score 0.58 (0.46–0.71) 0.64 (0.51–0.77) 0.70 (0.56–0.83) 1.70 0.209
Rate of complete mystical experience 33.3% (n=4) 45.5% (n=5) 30.0% (n=3)
Pharmacokinetics
AUC 0–12 h 77 (54–100) 124 (101–148) 151 (127–174) 41.8 <0.001
Maximum concentration (ng/mL) 16.9 (11.4–22.4) 28.1 (22.4–33.8) 35.9 (29.9–41.9) 17.5 <0.001

ANOVA: analysis of variance; AUC: area under the curve; CI: confidence interval; MEQ: Mystical Experience Questionnaire.

Results reported as estimated mean (95% CI) percentage of the maximum total score from the repeated measures ANOVA (RM-ANOVA).