Figure 8.

PFOS and PFHxS modulate expression of targets related to hepatic lipid metabolism and oxidative stress. Targeted graphs of gene expression data showing average fold change ± SEM; n = 4–6. Statistical significance was calculated using one-way ANOVA where *significant from the LFD control, ^#significant from the HFHC control, ^$significance between PFOS and PFHxS within each diet, and ^&significance between diet within each compound. A) Highlights diet-PFAS effects on genes related to lipid metabolism. B) Highlights diet-PFAS effects on genes related to oxidative stress.