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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: Acc Chem Res. 2020 Jul 13;53(9):1782–1790. doi: 10.1021/acs.accounts.0c00249

Figure 4.

Figure 4.

Cartoon representation of the guide strand’s kinks between nucleotides U6-G7 and U9-U10 in the crystal structure of Ago2 in complex with miR-20a.28 Reproduced with permission from ref 25.