Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 15;12:12853–12865. doi: 10.2147/CMAR.S273484

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Wang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Silencing of circ-PRKDC inhibits tumor growth in vivo. SW480 cells transfected with sh-NC or sh-circ-PRKDC were subcutaneously injected into nude mice. (A and B) Tumor volume was measured every 4 days. (C) After the mice were killed, the xenograft tumors were weighed. (D and E) The levels of circ-PRKDC, miR-198 and DDR1 in xenograft tumors were tested using qRT-PCR or Western blot. (F) The levels of CyclinD1, β-catenin and c-Myc in xenograft tumors were measured by Western blot. *P < 0.05, **P < 0.01, ****P < 0.0001.