Figure 7.
CircPVT1 expedited glucose consumption and lactate production in HCC cells via miR-377/TRIM23 axis. (A and B) The glucose consumption and lactate production levels in SNU-387 and Huh7 cells after circPVT1 knockdown were evaluated by specific kits. (C and D) The glucose consumption and lactate production levels in SNU-387 and Huh7 cells transfected with si-NC, si-circPVT1, si-circPVT1 + miR-377 inhibitor, or si-circPVT1 + miR-377 inhibitor were measured. (E–H) The glucose consumption and lactate production levels in SNU-387 and Huh7 cells transfected with miRNA NC, miR-377 mimic, miR-377 mimic + pcDNA-Control, or miR-377 mimic + pcDNA-TRIM23 were detected. *P<0.05.