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. 2020 Dec 16;12:12945–12956. doi: 10.2147/CMAR.S280478

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© 2020 Bu et al.

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CircPVT1 knockdown hindered tumor growth in vivo. Sh-circPVT1 or sh-NC transfected SNU-387 cells were injected into the nude mice. (A) Tumor volume was monitored every 4 days. (B) Tumor weight was examined after cells were injected for 27 days. (C–E) The levels of circPVT1, miR-377 and TRIM23 mRNA in the xenograft tumors were determined by qRT-PCR. (F) The protein level of TRIM23 in the xenograft tumors was detected by Western blot assay. *P<0.05.