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. 2020 Dec 16;12:619–627. doi: 10.2147/JEP.S283571

Table 1.

Effect of Aqueous and 80% Methanol Extracts of the Leaves of F. sur at Each Time Point of Five-hour Urine Volume in Rats

Group Volume of Urine (mL/100 g) Diuretic Action Diuretic Activity
1 h 2 h 3 h 4 h 5 h
DW/NC 1.83±0.32 2.53±0.42 0.43±0.21 0.62±0.31 0.52±0.23 1.00
FURO10 2.75±0.36 1.87±0.40 3.15±0.74a** 1.67±0.44 0.67±0.33 1.52 1.00
FSAE100 1.0±0.51 1.85±0.38 2.33±0.24 1.88±0.38 1.27±0.32 1.26 0.83
FSAE200 1.63±0.39 2.0±0.25 2.33±0.34 1.92±0.15 1.38±0.17 1.39 0.91
FSAE400 1.77±0.18 2.38±0.14 2.43±0.24a* 2.07±0.23 1.57±0.35 1.47 0.97
FSME100 2.4±0.77 2.27±0.59 1.97±0.67 0.92±0.41 0.47±0.21 1.25 0.82
FSME200 2.55±0.31 2.38±0.31 1.93±0.29 0.92±0.43 0.42±0.15 1.27 0.83
FSME400 2.47±0.19 2.42±0.47 1.95±0.35 1±0.34 0.77±0.32 1.41 0.92

Notes: Each value represents mean ± S.E.M; n=6; Analysis was performed by one way ANOVA; acompared to negative control; *p<0.05; **p<0.01; number followed by FURO, FSAE and FSME indicates dose/kg.

Abbreviations: DW, distilled water; NC, negative control; FURO, furosemide; FSAE, F. sur aqueous extract; FSME, F. sur methanol extract.