Table 1.
Group | Volume of Urine (mL/100 g) | Diuretic Action | Diuretic Activity | ||||||
---|---|---|---|---|---|---|---|---|---|
1 h | 2 h | 3 h | 4 h | 5 h | |||||
DW/NC | 1.83±0.32 | 2.53±0.42 | 0.43±0.21 | 0.62±0.31 | 0.52±0.23 | 1.00 | |||
FURO10 | 2.75±0.36 | 1.87±0.40 | 3.15±0.74a** | 1.67±0.44 | 0.67±0.33 | 1.52 | 1.00 | ||
FSAE100 | 1.0±0.51 | 1.85±0.38 | 2.33±0.24 | 1.88±0.38 | 1.27±0.32 | 1.26 | 0.83 | ||
FSAE200 | 1.63±0.39 | 2.0±0.25 | 2.33±0.34 | 1.92±0.15 | 1.38±0.17 | 1.39 | 0.91 | ||
FSAE400 | 1.77±0.18 | 2.38±0.14 | 2.43±0.24a* | 2.07±0.23 | 1.57±0.35 | 1.47 | 0.97 | ||
FSME100 | 2.4±0.77 | 2.27±0.59 | 1.97±0.67 | 0.92±0.41 | 0.47±0.21 | 1.25 | 0.82 | ||
FSME200 | 2.55±0.31 | 2.38±0.31 | 1.93±0.29 | 0.92±0.43 | 0.42±0.15 | 1.27 | 0.83 | ||
FSME400 | 2.47±0.19 | 2.42±0.47 | 1.95±0.35 | 1±0.34 | 0.77±0.32 | 1.41 | 0.92 |
Notes: Each value represents mean ± S.E.M; n=6; Analysis was performed by one way ANOVA; acompared to negative control; *p<0.05; **p<0.01; number followed by FURO, FSAE and FSME indicates dose/kg.
Abbreviations: DW, distilled water; NC, negative control; FURO, furosemide; FSAE, F. sur aqueous extract; FSME, F. sur methanol extract.