Table 2.

Effect of Aqueous and 80% Methanol Extracts of the Leaves of F. sur on Five-hour Cumulative Urine Volume in Rats

Group	Volume of Urine (mL/100gm)					Diuretic Index	Diuretic Activity
	1 h	2 h	3 h	4 h	5 h
DW/NC	1.83±0.32	4.37±0.22	4.80±0.30	5.42±0.35	5.93±0.30	1	0.65
FURO10	2.75±0.36	4.62±0.54	7.77±0.97a**,b*	9.43±0.80a***,b*	10.10±0.60a***,b*,c*,d*	1.52	1
FSAE100	1.00±0.52	2.85±0.59	5.18±0.50	7.07±0.68	8.33±0.50a**	1.26	0.83
FSAE200	1.63±0.40	3.63±0.53	5.97±0.36	7.88±0.30a*	9.27±0.37a***	1.39	0.91
FSAE400	1.77±0.18	4.15±0.24	6.58±0.24	8.65±0.37a**	10.22±0.17a***,b*,c**,d*	1.47	0.97
FSME100	2.40±0.77	4.67±0.37	6.63±0.41	7.55±0.23	8.02±0.15a*	1.25	0.82
FSME200	2.55±0.32	4.93±0.51B*	6.87±0.46	7.78±0.33a*	8.20±0.38a**	1.27	0.83
FSME400	2.47±0.19	4.88±0.53	6.83±0.47	7.83±0.57a*	8.60±0.42a***	1.41	0.92

Notes: Each value represents mean ±SEM (n=6). Analysis was performed by one-way ANOVA followed by Tukey's post hoc multiple comparison test; ^aagainst control, ^bagainst FSAE100, ^cagainst FSME100, ^dagainst FSME200; *p<0.05; **p<0.01; ***p<0.001; number followed by FURO, FSAE and FSME indicates dose/kg.

Abbreviations: DW, distilled water; NC, negative control; FURO, furosemide; FSAE, F. sur aqueous extract; FSME, F. sur methanol extract.