. 2020 Dec 16;12:619–627. doi: 10.2147/JEP.S283571

Table 3.

Effect of Aqueous and 80% Methanol Extracts of the Leaves of F. sur on Five-hour Urinary Electrolyte Excretion in Rats

Group	Urinary Electrolyte Concentration (mmol/L)			Saluretic Index			Na⁺/K⁺	Cl^–/ Na⁺+K⁺
Group	Na⁺	K⁺	Cl^–	Na⁺	K⁺	Cl^–	Na⁺/K⁺	Cl^–/ Na⁺+K⁺
DW/NC	15.33±2.38	27.68±5.80	20.73±3.43				0.55	0.48
FURO10	98.5±2.03^a*,^b,^e**	80.27±10.51^a*,^d,^e*	97.92±3.27^a*,^b,^e**	6.42	2.90	4.72	1.22	0.54
FSAE100	46.17±5.12^a***	39.33±8.79	52.63±7.83^a**	3.01	1.42	2.54	1.17	0.61
FSAE200	55.67±4.63^a***	58.89±4.48	46.77±3.91^a*	3.63	2.13	2.26	0.95	0.41
FSAE400	82.33±5.61^a*,^b,^e**	44.32±4.96	74.93±3.88^a**,^c,^e***	5.37	1.60	3.61	1.86	0.59
FSME100	39.83±1.74^a**	39.14±2.97	33.52±2.71	2.60	1.41	1.62	1.02	0.42
FSME200	60.5±2.74^a*,^e	51.59±6.70	51.90±6.36^a**	3.95	1.86	2.50	1.17	0.46
FSME400	67.33±3.56^a*,^b,^e***	62.58±13.33	55.38±9.36^a**	4.39	2.26	2.67	1.08	0.43

Notes: Each value represents mean ±SEM (n=6). Analysis was performed by one way ANOVA followed by Tukey's post hoc multiple comparison test; ^aagainst control, ^bagainst FSAE100, ^cagainst FSAE200, ^dagainst FSAE400, ^eagainst FSME100; *p<0.05; **p<0.01; ***p<0.001; number followed by FURO, FSAE and FSME indicates dose/kg.

Abbreviations: DW, distilled water; NC, negative control; FURO, furosemide; FSAE, F. sur aqueous extract; FSME, F. sur methanol extract.