Table 3.
Associations between maternal preconception serum POPs and gravid conditions.
Chemical | GDM (N = 28) | HTN (N = 27) | ||
---|---|---|---|---|
Model A OR (95% CI) | Model B OR (95% CI) | Model A OR (95% CI) | Model B OR (95% CI) | |
OCPs | ||||
HCB | 0.96 (0.63,1.46) | 0.97 (0.60,1.57) | 0.64 (0.37,1.11) | 0.74 (0.40,1.36) |
β-HCH | 0.58 (0.17,2.01) | 0.34 (0.07,1.67) | 0.29 (0.04,2.15) | 0.43 (0.06,3.21) |
Oxychlordane | 1.07 (0.73,1.56) | 1.26 (0.76,2.08) | 0.59 (0.35,1.01) | 0.61 (0.34,1.10) |
p,p’-DDE | 1.11 (0.79,1.55) | 1.20 (0.72,2.02) | 0.62 (0.34,1.11) | 0.68 (0.33,1.40) |
p,p’-DDT | 0.94 (0.60,1.48) | 1.01 (0.55,1.85) | 0.24 (0.05,1.11) | 0.27 (0.04,1.73) |
trans-Nonachlor | 0.99 (0.67,1.46) | 1.03 (0.67,1.58) | 0.55 (0.28,1.07) | 0.58 (0.28,1.21) |
PBDE congeners | ||||
28 | 0.81 (0.48,1.37) | 0.47 (0.17,1.26) | 0.80 (0.47,1.38) | 0.71 (0.28,1.79) |
47 | 0.83 (0.51,1.35) | 0.32 (0.10,1.01) | 0.98 (0.65,1.48) | 1.86 (0.55,6.27) |
85 | 0.94 (0.60,1.48) | 0.71 (0.23,2.24) | 0.83 (0.47,1.48) | 0.61 (0.17,2.21) |
99 | 0.78 (0.41,1.45) | 0.44 (0.15,1.33) | 0.91 (0.56,1.47) | 0.96 (0.42,2.19) |
100 | 1.15 (0.82,1.61) | 2.22 (0.96,5.17) | 0.85 (0.51,1.41) | 0.69 (0.23,2.06) |
153 | 1.37 (1.02,1.84) | 1.79 (1.18,2.74) | 0.81 (0.47,1.41) | 0.84 (0.46,1.52) |
154 | 0.99 (0.66,1.49) | 1.04 (0.34,3.17) | 0.84 (0.48,1.46) | 0.59 (0.15,2.33) |
HCB, hexachlorobenzene; β-HCH, β-hexachlorocyclohexane; γ-HCH, γ-hexachlorocyclohexane; o,p′ DDT, 1,1,1-Trichloro-2-2(o-chlorophenyl)-2-(p-chlorophenyl)ethane; p,p′-DDE, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene; p,p′-DDT, 1,1,1-Trichloro-2-2(o-chlorophenyl)-2-(p-chlorophenyl)ethane; OCPs, organochlorine pesticides; PBDE, polybrominated diphenyl ether; IQR, interquartile range; LOD, limit of detection; GDM, gestational diabetes mellitus; HTN, gestational hypertension.
Model A, multiple logistic regression models were adjusted for serum lipids.
Model B, multiple logistic regression models were adjusted for serum lipids, age, BMI, non-white race, smoking, and the sum of remaining chemicals in the relevant class of compounds.