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. 2020 Dec 13;23(2):141. doi: 10.3892/mmr.2020.11780

Figure 4.

Figure 4.

circARRDC3, miR-375 and KLF4 are dysregulated in AR tissues. (A) circARRDC3, (B) miR-375 and (C) KLF4 expression levels were detected by reverse transcription-quantitative PCR in nasal mucosa of normal healthy subjects (n=20) and patients with AR (n=20). (D) Pearson's correlation analysis indicated a negative correlation between circARRDC3 and miR-375 expression in the nasal mucosa of patients with AR (n=20). (E) Pearson's correlation analysis indicated a negative correlation between KLF4 and miR-375 expression in the nasal mucosa of patients with AR (n=20). (F) Pearson's correlation analysis indicated a positive correlation between circARRDC3 and KLF4 expression in the nasal mucosa of patients with AR (n=20). *P<0.05 vs. normal healthy subjects. ARRDC3, arrestin domain-containing 3; circ-, circular RNA; miR, microRNA; KLF4, krueppel-like factor 4; AR, allergic rhinitis.