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. 2020 Dec 10;23(2):128. doi: 10.3892/mmr.2020.11767

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Gene expression in different treatment groups. (A) Gli1, Gli2, NANOG and MDR1 expression were decreased after treatment with GANT61 in SKOV3 cells. mRNA expression of Gli1 and Gli2 did not significantly change in SKOV3 cells, while mRNA expression of NANOG and MDR1 increased slightly after treatment with SHH. (B) The expression of Gli1, Gli2, NANOG and MDR1 in SKOV3 cells after treatment with GANT61 and SHH was detected by western blotting. *P<0.05 vs. control; ^#P<0.05 vs. control. EOC, epithelial ovarian cancer; NANOG, homeobox protein NANOG; MDR1, p-glycoprotein; SHH, recombinant human sonic HH.