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Successful establishment of the in vitro model of OA. CHON-001 cells were treated with IL-1β (10 ng/ml) for 24 h to establish an in vitro model of OA. Protein expression levels were (A) determined by western blotting, and (B) aggrecan and (C) MMP13 were semi-quantified. β-actin was used as an internal control. **P<0.01 vs. control group. IL-1β, interleukin-1β; OA, osteoarthritis.
