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SNHG16 knockdown inhibits IL-1β-mediated activation of p21 and cleaved caspase-3. Protein expression levels were (A) determined by western blotting, and (B) p21 and (C) cleaved caspase-3 were semi-quantified. **P<0.01 vs. control group; ##P<0.01 vs. IL-1β group. IL-1β, interleukin 1β; siRNA, small interfering RNA; SNHG16, small nucleolar RNA host gene 16.
