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. 2020 Dec 10;23(2):130. doi: 10.3892/mmr.2020.11769

Figure 6.

Figure 6.

miR-182-5p reverses the effects of BNIP3 on radioresistance of nasopharyngeal carcinoma cells by affecting cell invasion and apoptosis. (A) Invasion was assessed in the transfected 5-8F and 5-8F-R cells treated with 4 Gy IR. (B) Flow cytometry was used to measure the apoptosis of 5-8F and 5-8F-R cells treated with 4 Gy IR. Protein expression levels of (C) invasion-related and (D) apoptosis-related proteins in 5-8F and 5-8F-R cells were assessed following treatment with 4 Gy IR. *P<0.05, **P<0.001 vs. NC; ##P<0.001 vs. si-BNIP3 group in 5-8F cells; $$P<0.001 vs. BNIP3 OE group in 5-8F-R cells. BNIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; NC, negative control; miRNA/miR, microRNA; si-, small interfering RNA; OE, overexpression; IR, irradiation.