Table IV.
Melanoma tumor volume in nude mice before and 48 h after injection of anti-tumor drugs
Tumor volume, | ||||||
---|---|---|---|---|---|---|
Item | Primary tumor volume, mm3 | First | Second | Third | Fourth | Fifth |
T-La (FS) | 21.1022± | 25.3020± | 19.8162± | 20.6351± | 27.0552± | 134.1800± |
2.48719a | 3.04705b | 2.69010a,b | 3.42328a | 5.39173a | 14.22572a | |
RGD-T-L (FS) | 38.9477± | 38.5640± | 25.6673± | 12.9156± | 32.1026± | 82.8592± |
11.16416a | 6.22073b | 1.93695a | 15.98864a | 11.98846a | 25.75526a | |
T-La | 26.6849± | 33.3320± | 19.5228± | 20.0724± | 32.6486± | 100.7889± |
5.36854a | 8.72730b | 3.78134a,b | 3.76676a | 5.07784a | 10.08681a | |
RGD-T-La | 24.3425± | 27.9720± | 10.7225± | 18.8990± | 32.6512± | 83.0283± |
3.35537a | 5.69018b | 2.03661b | 2.16945a | 5.11254a | 18.52589a | |
Cisplatin positive control | 23.9659± | 34.4100± | 14.2439± | 13.1352± | 3.5965± | / |
5.18682a | 7.04033b | 4.04242a,b | 5.14370a | 4.20833b | ||
PBS blank control | 32.2281± | 62.0960± | 25.9056± | 25.8578± | 22.9230± | 114.2617± |
2.09646a | 5.50607a | 7.16902a | 4.13521a | 3.37649a | 13.95786a |
Data are presented as mean ± SE, n=6.
P<0.05
P<0.001 and a,bP>0.05 vs. PBS blank control.