Table 3.

Concordance of diagnoses primarily investigated by telepathology (TP) with a second opinion (SO) in Germany. Diagnostic evaluation: 1-completely identical diagnosis between TP and SO, 2-mild discordances (e.g. in subtype of inflammation or grading of cancer), 3-identical in benign/malignant group, but other entity of disease, 4-Diagnosis of TP was false malignant, 5-diagnosis of TP was false benign, 6- primary diagnosis by TP was not possible

	Sent for second opinion	Kind of concordance	n/%	Number of cases in which immunohistochemistry (IHC) or special stains (S) were needed
Benign diseases
390	107	1	50 (46.7%)	S: 14, IHC 3
		2	23 (21.4%)	S: 8, IHC: 3
		3	22 (20.5%)	S: 11, IHC: 7
		4	6 (5.6%)	S: 3, IHC: 1
		5	0
		6	6 (5.6%)	S: 3
Malignant diseases
96	72	1	21 (29.1%)	S: 1, IHC: 17
		2	16 (22.2%)	S: 1, IHC: 14
		3	18 (25.0%)	IHC: 18
		4	0
		5	11 (15.3%)	S: 2, IHC: 9
		6	6 (8.3%)	IHC: 3