Table 6.
EGTI score of histopathological findings in the renal tissues of rats
| Group |
Endothelial lesions |
Glomerular lesions |
Tubular lesions |
Interstitial lesions |
| Normal control |
0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 |
| Sham control | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 |
| IR-group | 3.82±0.40a,b | 3.00±1.44a,b | 3.17±0.92a,b | 2.33±0.96a,b |
| MO Low dose | 1.67±0.48c | 0.70±0.72c | 3.00±1.44c | 1.22±0.42c |
| MO High dose | 1.00±0.00c | 1.39±0.78c | 3.17±0.92c | 1.17±0.38c |
| Vit. C group | 1.26±0.59c | 1.11±0.75 | 2.33±0.96c | 0.70±0.47c |
Values are expressed as mean±standard deviation (n = 7)
a
Significant (p<0.05) compared to normal controls
b
Significant (p<0.05) compared to sham controls
c
Significant (p<0.05) compared to IR group
A = Normal control; B = Sham control; C = IR group; D = IR + MO (200 mg/kg); E = IR + MO (400 mg/kg); F = IR + Vit. C (200 mg/kg)