Table 1.
Patients Characteristics
| All Patients (n=353) | ANA (n=177) | SITA (n=176) | ||
|---|---|---|---|---|
| Age (yrs) | 68 (10) | 68 (10) | 68 (9) | |
| Men (%) | 214 (61) | 110 (62) | 104 (59) | |
| Body mass index | 26.17 (3.79) | 26.49 (4.04) | 25.85 (3.50) | |
| Smoking | Current (%) | 54 (15) | 30 (17) | 24 (14) |
| Past (%) | 141 (40) | 62 (35) | 79 (45) | |
| Hypertension (%) | 270 (76) | 137 (77) | 133 (76) | |
| Established CAD (%) | 159 (45) | 80 (45) | 79 (45) | |
| Taking moderate statin (%) | 278 (79) | 142 (80) | 136 (77) | |
| Taking aspirin (%) | 153 (43) | 84 (47) | 69 (39) | |
| Taking thiazoridine (%) | 56 (16) | 25 (14) | 31 (18) | |
| Taking SGLT2-inhibitor (%) | 56 (16) | 28 (16) | 28 (16) | |
| Taking previous DDP-4 inhibitor (%) | 290 (82) | 145 (82) | 145 (82) | |
| Total cholesterol (mg/dL) | 185 (169–204) | 188 (171–207) | 183 (167–199) | |
| Triglyceride (mg/dL) | 120 (86–167) | 129 (95–186) | 114 (80–159) | |
| HDL-cholesterol (mg/dL) | 52 (45–61) | 52 (45–60) | 53 (45–62) | |
| LDL-cholesterol (mg/dL) | 108 (96–122) | 112 (97–123) | 106 (94–121) | |
| Fasting blood sugar (mg/dL) | 133 (116–118) | 136 (115–116) | 128 (117–153) | |
| Hemoglobin A1C (%) | 6.9 (6.4–7.4) | 7.0 (6.4–7.6) | 6.8 (6.4–7.3) | |
| WBC (/mm3) | 6100 (5200–7200) | 6365 (5325–7500) | 5900 (4900–7000) | |
| hs-CRP (mg/L) | 0.658 (0.316–1.475) | 0.675 (0.360–1.450) | 0.608 (0.307–1.515) | |
| IL6 (ng/mL) | 2.1 (1.5–3.2) | 2.2 (1.4–3.4) | 2.1 (1.5–2.8) | |
Note: Variables are presented as mean (standard deviations) or medians with interquartile ranges.
Abbreviations: ANA, anagliptin; CAD, coronary artery disease; DDP-4, dipeptidyl peptidase-4; HDL, high-density lipoprotein; hs-CRP, high-sensitive C-reactive protein; IL, interleukin; LDL, low-density lipoprotein; SITA, sitagliptin; SGLT-2, sodium glucose co-transporter 2; WBC, white blood cells.