Table 2.
Demographics and clinical characteristics of the subjects with MTHFR T-carrier and C-homozygous.
| TT+CT | CC | χ2/t | P-Value | |
|---|---|---|---|---|
| (n = 149) | (n = 79) | |||
| Gender (male/female) | 69/80 | 19/60 | 10.792 | 0.001 |
| Age (year) | 29.89 ± 6.97 | 32.22 ± 7.06 | −2.384 | 0.018 |
| Years of education | 14.07 ± 4.71 | 13.75 ± 4.56 | 0.504 | 0.615 |
| Ethnic Han (%) | 100% | 100% | ||
| Dextromanuality (%) | 100% | 100% | ||
| eTIV (mm3) | 1.2570E6 ± 3.4432E5 | 1.2426E6 ± 1.2570E6 | 0.318 | 0.751 |
| HAMD score | 14.107 ± 12.044 | 12.165 ± 12.614 | 1.140 | 0.255 |
| HAMA score | 13.738 ± 11.847 | 11.810 ± 12.1540 | 1.159 | 0.248 |
eTIV, Estimated Total Intracranial Volume; HAMD, Hamilton Depression-17 item scale; HAMA, Hamilton Anxiety Scale; T-carrier, The TT genotype or CT genotype of MTHFR C677T polymorphism; C-homozygous, CC genotype of MTHFR C677T polymorphism.
Data are means ± standard deviation for age, years of education, eTIV, HAMD, and HAMA scores.
The P-value for distributions of gender was obtained by chi-square test. The P-values for comparisons of age, years of education, eTIV, HAMD, and HAMA scores, were obtained using independent t-tests.