TABLE 3.
Left-ventricular function metrics and hemodynamic correlations
| HR (BPM) | CO (L/min) | EF (%) | EDV / BSA (ml/m2) | ESV / BSA (ml/m2) | SV / BSA (ml/m2) | Myocardial mass / BSA (g/m2) | |
|---|---|---|---|---|---|---|---|
| AAo Mean Velocity (m/s) | 0.18 | 0.40 | −0.05 | 0.17 | 0.16 | 0.15 | 0.11 |
| Arch Mean Velocity (m/s) | 0.08 | 0.38 | −0.07 | 0.31 | 0.27 | 0.28 | 0.04 |
| DAo Mean Velocity (m/s) | −0.02 | 0.30 | −0.06 | 0.37 | 0.31 | 0.35 | −0.05 |
| AAo Vmax (m/s) | 0.00 | 0.15 | 0.03 | 0.07 | 0.04 | 0.08 | 0.27 |
| Arch Vmax (m/s) | 0.01 | 0.34 | −0.06 | 0.31 | 0.27 | 0.28 | 0.11 |
| DAo Vmax (m/s) | −0.02 | 0.29 | −0.02 | 0.35 | 0.28 | 0.34 | 0.01 |
| AAo Mean 3D-WSS (Pa) | 0.22 | 0.32 | −0.05 | 0.09 | 0.10 | 0.06 | 0.03 |
| Arch Mean 3D-WSS (Pa) | 0.06 | 0.38 | −0.04 | 0.34 | 0.28 | 0.33 | 0.07 |
| DAo Mean 3D-WSS (Pa) | 0.00 | 0.29 | −0.03 | 0.37 | 0.30 | 0.35 | −0.07 |
| AAo WSSmax (Pa) | 0.18 | 0.16 | 0.03 | −0.03 | −0.03 | −0.01 | 0.13 |
| Arch WSSmax (Pa) | −0.02 | 0.31 | 0.00 | 0.26 | 0.21 | 0.26 | 0.11 |
| DAo WSSmax (Pa) | −0.02 | 0.28 | −0.02 | 0.37 | 0.29 | 0.36 | −0.01 |
| AAo Median Positive Helicity (m/s2) | 0.14 | 0.39 | −0.07 | 0.21 | 0.19 | 0.18 | 0.11 |
| AAo Median Negative Helicity (m/s2) | −0.19 | −0.32 | −0.03 | −0.12 | −0.08 | −0.13 | 0.01 |
| Arch Median Positive Helicity (m/s2) | 0.08 | 0.35 | −0.14 | 0.36 | 0.35 | 0.29 | 0.07 |
| Arch Median Negative Helicity (m/s2) | 0.01 | −0.27 | 0.15 | −0.36 | −0.35 | −0.29 | −0.03 |
| DAo Median Positive Helicity (m/s2) | 0.01 | 0.30 | −0.09 | 0.34 | 0.30 | 0.30 | 0.00 |
| DAo Median Negative Helicity (m/s2) | 0.02 | −0.28 | 0.10 | −0.37 | −0.33 | −0.33 | 0.00 |
Note: Pearson correlation coefficients (r) are presented between left-ventricular function metrics and hemodynamic parameters (velocity, 3D-WSS) from 4D-flow MRI of the aorta, with all metrics calculated for each subject. Yellow entries signify P < .05, orange signify P < .01, and red signifies P < .001. Cardiac output is significantly correlated with velocity and 3D-WSS in all aorta regions, and the volume metrics (end-diastolic volume, end-systolic volume, and stroke volume) are significantly correlated with the velocity and 3D-WSS in the arch and DAo. To reduce the influence of noise, maximum velocity was filtered as described in the Methods section, and the maximum 3D-WSS is the 98th percentile of the 3D-WSS distribution in that region.