Figure 3.

Assessments of inflammation in renal tissues of diabetic mice with baicalin treatment

a: Representative Immunohistological staining for CD3, CD68 and P65 in kidney tissues of control, DM and DM + Baicalin treated mice. b-d: Bar charts showing the percentage of CD3⁺ (B), CD68⁺ (C) and P65⁺ (D) cells in kidney tissue sections of control, DM and DM + Baicalin treated mice. e: RT-qPCR showing extent of TNF-ɑ, MCP-1 and NLRP3 expressions in control, DM and DM + Baicalin kidneys. f-g: Western blot showing extent of CD3, CD68, P65 and IĸB-ɑ expressions. Scale bars = 100 µm in A. *p < 0.05, **p < 0.01, ***p < 0.001 compared with control group; #p < 0.05, ##p < 0.01, ###p < 0.001 compared with DM group.