Figure 9.

miR-221 upregulation and CHD8 downregulation suppressed cell cycle blockade of SHEDs. (a) Cell cycle analysis produced by flow cytometry in SHEDs. (b) Cell cycle distribution in percentages of the different groups. *, p < 0.05 vs. the mimic-NC group; #, p < 0.05 vs. the inhibitor-NC group; &, p < 0.05 vs. the si-NC group; @, p < 0.05 vs. the miR-221 inhibitor group. Measurement data were expressed as mean ± standard deviation. Data at different time points were compared by repeated measurement ANOVA, followed by Bonferroni post-hoc test. The experiment was repeated three times. miR-221, microRNA-221; CHD8, Chromodomain-Helicase-DNA-binding protein 8; SHEDs, Stem cells from Human Exfoliated Deciduous teeth; NC, negative control