Figure 2.

PPE treatment reduced CNS inflammation. EAE mice treated with PBS or PPE described in Figure 1(a) were sacrificed at d 24 p.i., and the brain and spinal cord were harvested. (a) Total number of mononuclear cells (MNCs) in CNS. (b–i) The percentages and absolute numbers of CD45⁺, CD45⁺CD11b⁺, CD11c⁺, CD11c⁺CD80⁺, CD11c⁺CD86⁺, CD4⁺ cells were measured by flow cytometry. Data are expressed as the mean ± SEM (n = 3 for each group). **p < 0.01, determined by unpaired Student’s t-test