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. 2020 Nov 13;11:572387. doi: 10.3389/fphar.2020.572387

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Copyright © 2020 Wang, Yang, Zhong, Jiang, Zhang, Kwan and Su

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Zanthoxylum bungeanum Maxim (ZBM) treatment reduces body weight and induces apoptosis in adipose tissues in the HFD-induced obesity (DIO) mouse model. (A) Picture of the CD-fed and the HFD-fed mice. HFD, high-fat diet; CD, comparable control diet. (B) Body weight of DIO mice after ZBM treatments. Expression of cleaved PARP in (C) subcutaneous adipose tissue and (D) visceral adipose tissue in the DIO mice after ZBM treatments. The data are shown as the means ± SEM, n = 6 mice in each group. *p < 0.05 compared to vehicle control group.