FIGURE 2.

Effect of CD treatment on sterile inflammation in mice with APAP-induced ALI. (A–C) Liver tissue collected from the mice 6 h after APAP challenge and used for measurement of TNF-α, IL-6, and IL-1β concentrations. (D–H) Effects of CD on the protein abundance of JNK and p38 MAPK in mice with APAP-induced ALI. Similar results were obtained from three independent experiments. All data are presented as means ± SEM (n = 10 in each group). *p < 0.05 and **p < 0.01 vs. control group; ^# p < 0.05 and ^## p < 0.01 vs. APAP group.