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. 2020 Nov 13;11:601716. doi: 10.3389/fphar.2020.601716

FIGURE 3.

FIGURE 3

Effect of CD treatment on the APAP-induced NLRP3 inflammasome signaling pathway in ALI mice. Liver tissue was collected 6 h after APAP challenge and analyzed by western blot. (A–E) Effects of CD treatment on protein abundance of NLRP3, cleaved-caspase-1, mature-IL-1β, and HMGB1 in mice with APAP-induced ALI. Similar results were obtained from three independent experiments. All data are presented as means ± SEM (n = 10 in each group). *p < 0.05 and **p < 0.01 vs. control group; # p < 0.05 and ## p < 0.01 vs. APAP group.