Figure 6.

Circ_0008450 silence prevented the migration of keratinized epithelial cell and EMT process via the up-regulation of Runx3. Keratinized epithelial cells transfected with sh-circ_0008450 (sh-circ_0008450) or sh-Runx3 (sh-Runx3) or both were applied for the detection of migration and EMT process. (a) Relative migratory rate was assessed by migration assay. * p < 0.05, ** p < 0.01 or *** p < 0.001. (b-c) EMT marker E-cadherin, Vimentin, Fibronectin, and ZO-1 were assessed by Western blot. ** p < 0.01 or *** p < 0.001