Figure 1.

miR-877 is poorly expressed in LC. (a). ACP5 could bind to multiple miRs at the 3ʹUTR region; (b). miR-877 is downregulated in lung adenocarcinoma tissues, * p < 0.05, ** p < 0.01; (c). miR-877 binds to ACP5 mRNA and inhibits its activity; (d). miR-877 is downregulated in LC tissues, n = 80; (e). The miR-877 level is negatively correlated to the ACP5 level in LC patients, n = 80; (f). Relative miR-877 expression in L9981, 95 C, H1299, A549, SPC-A-1 and BEAS-2B cell lines, n = 3; All * p < 0.05. miR-877, microRNA-877; LC, lung cancer; ACP5, tartrate resistant acid phosphatase 5