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. 2020 Dec 17;14:5547–5558. doi: 10.2147/DDDT.S280922

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© 2020 Li et al.

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OI reduces the release of inflammatory factors in vitro. The RAW264.7 cells were pretreated with OI (62.5µM, 125µM), followed by LPS (1µg/mL) stimulation. The level of IL-1β, IL-6, and TNF-α at 6 h was detected by qPCR (A–C, n=3). IL-1β, IL-6, and TNF-α contents in the supernatant were determined 24 h after LPS stimulation (D–F, n=3). The results are presented as means ±SD. ^#P < 0.05 compared with the group only treated by 1μg/mL LPS.