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. Author manuscript; available in PMC: 2020 Dec 21.
Published in final edited form as: Gastroenterology. 2020 Mar 26;159(1):139–147. doi: 10.1053/j.gastro.2020.03.039

Table 3.

Association of Remission Definitions at the End of the CALM Study With Disease Progression Based on Multivariate Penalized Cox Regression

Variable aHR (95% CI)
Deep remission 0.19 (0.08–0.31)
Endoscopic remission 0.41 (0.24–0.60)
Clinical remission 0.40 (0.26–0.57)

NOTE. Multivariate cox models adjusted for CALM treatment arm, age, sex, disease duration, baseline C-reactive protein, baseline calprotectin, disease location, smoking, prior surgery, and history of stricturing disease.