Figure 1.

The mutational landscape of 225 Chinese patients with ESCC. (A) The top 40 mutated genes. (B) Commonly mutated pathways. The X-axis displays each case sample and the Y-axis displays each mutated gene. The bar graph above shows the tumor mutational burden for each sample. The mutation frequency of each mutated gene is shown on the right. Green represents substitution or insertion-deletion mutations, red represents gene amplification mutations, blue represents homozygous gene deletion mutations, yellow represents fusion/rearrangement mutations, and purple represents truncation mutations.