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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Curr Opin Solid State Mater Sci. 2020 Nov 29;25(1):100873. doi: 10.1016/j.cossms.2020.100873

Figure 5.

Figure 5.

Nanotopography induces F-actin polymerization in a curvature-dependent manner. (a) F-actin, probed by Lifeact-RFP, and FBP17 preferentially accumulate to the ends of nanobars, which represent high curvature locations. Scale bars, 10 μm. (b) SEM images of a vertical quartz nanopillar array used in this research and cells growing on nanopillars. Left: scale bar 2 μm. Right: scale bar 5 μm. (c) Anti-paxillin staining of focal adhesion and phalloidin staining of F-actin in U-2 OS cells growing on the flat surface and nanopillars. Scale bars, 10 μm. (a-c) The figures are adapted with permission from [89]. Copyright 2019, PNAS.