Table 1. Nuclear import receptors in the Karyopherin family of proteins.
Human importins (abbreviations/alternative names) | S. cerevisiae importins (alternative names) | NLS |
---|---|---|
Importin-α/Importin-β (Impα/Impβ/Kapα/Kapβ1) | Kap60/Kap95 | Classical-NLS |
Karyopherin-β2 (Kapβ2/Transportin-1) | Kap104 | PY-NLS |
Importin-4 (Imp4/RanBP4) | Kap123 | ND# |
Importin-5 (Imp5/Kapβ3, Impβ3, RanBP5) | Kap121 (Pse1) | IK-NLS |
Importin-7 (Imp7/RanBP7) | Kap119 (Nmd5) | ND |
Importin-8 (Imp8/RanBP8) | Kap108 (Sxm1) | ND |
Importin-9 (Imp9/RanBP9) | Kap114 (Kapβ) | ND |
Importin-11 (Imp11/RanBP11) | Kap120 | ND |
Transportin-3 (TNPO3/Trn-SR, Imp12) | Kap122 (Pdr6) | RS-NLS |
Importin-13* (Imp13/Kap13, RanBP13) | ND | |
Exportin-4* (Exp4) | ND |
#ND: not determined; * bidirectional transport receptor.