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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Nat Rev Genet. 2020 Feb 7;21(4):243–254. doi: 10.1038/s41576-020-0210-7

Fig. 1 |. Core and dispensable genomes.

Fig. 1 |

a | Bacterial and other prokaryotic genomes consist predominantly of genes, with little intergenic sequence. The core genome of a species consists of genes shared by all strains. The dispensable genome is made up of genes shared by some but not all strains (accessory genes) and genes present in only one strain (unique genes). Together, the core and dispensable genomes make up the pan-genome. b | Eukaryotic genomes are not highly variable in their genic content. Pan-genomes consider intergenic sequence as well as genes, resulting in an ordered pan-genome of all sequence present in at least one individual.