. Author manuscript; available in PMC: 2020 Dec 21.

Published in final edited form as: J Biol Rhythms. 2020 Jan 28;35(2):214–222. doi: 10.1177/0748730419900866

Table 3.

User choices for generating synthetic data in CIRCADA-S. To run with all replications having identical period (and other characteristics), set SD of periods to zero; a non-zero value results in a normally distributed set of periods with indicated mean and SD. Noise “scaled by the signal” is generated by taking Gaussian noise and multiplying pointwise by the signal, to imitate experimental data in which noise increases in proportion with the signal value.

Parameter	Range of values
Sampling interval	0.125, 0.25, 0.5, 1, or 2 h
Mean period	20–28 hours
Standard deviation (SD) of periods	0–2 hours
Peak location	0–1 (any proportion of a cycle)
Amplitude	0–3 (arbitrary units)
Waveform	Sinusoid, square wave, or asymmetric triangular wave
Noise standard deviation	0–3 (arbitrary units)
Noise type	Gaussian, pink, brown, or scaled by the signal
Trend	None, linear, or quadratic
# of samples	1–1000