TABLE 1.
Blood pressure and pulse wave velocity parameters corrected for mean arterial pressure
| Heart rate (HR) | HR dependence | ||||||
| 300 bpm | 350 bpm | 400 bpm | 450 bpm | 500 bpm | Slope | P | |
| Mean arterial pressure (MAP) | |||||||
| 70 mmHg | |||||||
| SBP (mmHg) | 96 ± 2 | 93 ± 2 | 92 ± 2 | 91 ± 2 | 89 ± 2 | −3.6 ± 0.4 | <0.001 |
| DBP (mmHg) | 53 ± 1 | 54 ± 1 | 56 ± 1 | 56 ± 1 | 57 ± 1 | 1.8 ± 0.2 | <0.001 |
| PWVTT (m/s) | 3.46 ± 0.15 | 3.46 ± 0.15 | 3.47 ± 0.15 | 3.47 ± 0.15 | 3.46 ± 0.15 | 0.01 ± 0.02 | 0.708 |
| PWVdist (m/s) | 3.39 ± 0.14 | 3.36 ± 0.13 | 3.51 ± 0.13 | 3.60 ± 0.13 | 3.63 ± 0.13 | 0.15 ± 0.04 | <0.001 |
| 100 mmHg | |||||||
| SBP (mmHg) | 136 ± 1 | 132 ± 1 | 130 ± 1 | 126 ± 1 | 124 ± 1 | −5.7 ± 0.3 | <0.001 |
| DBP (mmHg) | 77 ± 1 | 80 ± 1 | 81 ± 1 | 83 ± 1 | 84 ± 1 | 3.3 ± 0.2 | <0.001 |
| PWVTT (m/s) | 3.65 ± 0.14 | 3.70 ± 0.14 | 3.74 ± 0.14 | 3.84 ± 0.14 | 3.86 ± 0.14 | 0.12 ± 0.01 | <0.001 |
| PWVdist (m/s) | 3.92 ± 0.11 | 4.12 ± 0.11 | 4.31 ± 0.11 | 4.30 ± 0.11 | 4.44 ± 0.11 | 0.24 ± 0.03 | <0.001 |
| 130 mmHg | |||||||
| SBP (mmHg) | 172 ± 2 | 169 ± 2 | 167 ± 2 | 164 ± 2 | 161 ± 2 | −5.4 ± 0.3 | <0.001 |
| DBP (mmHg) | 103 ± 1 | 105 ± 1 | 107 ± 1 | 108 ± 1 | 110 ± 1 | 3.4 ± 0.2 | <0.001 |
| PWVTT (m/s) | 4.22 ± 0.15 | 4.28 ± 0.15 | 4.36 ± 0.15 | 4.46 ± 0.15 | 4.53 ± 0.15 | 0.17 ± 0.02 | <0.001 |
| PWVdist (m/s) | 4.98 ± 0.13 | 5.00 ± 0.13 | 5.21 ± 0.13 | 5.23 ± 0.13 | 5.26 ± 0.13 | 0.16 ± 0.04 | <0.001 |
| MAP dependence | |||||||
| Slope | |||||||
| SBP (mmHg) | 127 ± 2 | 126 ± 2 | 124 ± 2 | 122 ± 2 | 121 ± 2 | ||
| DBP (mmHg) | 83 ± 1 | 85 ± 1 | 85 ± 1 | 87 ± 1 | 88 ± 1 | ||
| PWVTT (m/s) | 1.3 ± 0.2 | 1.4 ± 0.2 | 1.5 ± 0.2 | 1.6 ± 0.2 | 1.8 ± 0.2 | ||
| PWVdist (m/s) | 2.6 ± 0.3 | 2.7 ± 0.3 | 2.8 ± 0.3 | 2.7 ± 0.3 | 2.7 ± 0.3 | ||
Values denote mean ± standard error. SBP, DBP, transit time pulse wave velocity (PWVTT), and distensibility-based pulse wave velocity (PWVdist) as a function of mean arterial pressure (MAP, vertically) and heart rate (HR, horizontally). Note that values in each row are corrected to a fixed mean arterial pressure of 70, 100, or 130 mmHg. Hence, as expected, the decreasing pulse pressure with increasing heart rate leads to a decrease in SBP and an increase in DBP with heart rate. HR and MAP dependences are given in units of measurement per 100 bpm or per 100 mmHg, respectively. MAP dependences were calculated at 100 mmHg. All values are corrected for age. P denotes P-value for slope. For MAP dependence, all P < 0.001.