Figure 1.
The effect of genistein and BKCa channels on Ox-LDL-induced VSMC proliferation. Cell proliferation was determined by CCK-8. (a) Cell proliferation curves of different treatments. (b) The cell proliferation rate of different groups at 72 h. Ox-LDL increases the proliferation of primary cultured VSMCs. Genistein and IBTX inhibit Ox-LDL-increased proliferation, while NS1619 increases proliferation. DMSO had no significant effect. Results were presented as the mean ± SD from three independent experiments. ##P < 0.01 vs. control, ∗P < 0.05 and ∗∗P < 0.01 vs. Ox-LDL.