FIGURE 1.
Effect of ABT-702 treatment on LV function and morphology in obese ZSF1 rats. Panels A-H, Summary data of parameters obtained during LV pressure measurement in lean (LN) and obese (OB) ZSF1 rats treated with ABT-702 or vehicle (n = 4 in each group). Panel I, Representative Masson’s Trichrome images and summary data of quantification of myocardial surface area in LV sections in lean and in obese ZSF1 rats with or without ABT-702 treatment (n = 4 in each group). Bar = 100 μm. *P < .05 lean vs obese ZSF1 rats. #P < .05 between obese vehicle and obese ABT-702 treated rats