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. 2020 Dec 17;5(6):e877. doi: 10.1097/PR9.0000000000000877

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Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain.

This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0 (CC BY-ND) which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author.

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Figure 3. — (A) Change in the pain score compared with baseline during and after treatment with tapentadol (light blue circles) and placebo (dark blue squares). The gray bar indicates the treatment period. Tapentadol significantly reduced spontaneous pain scores compared with placebo (P = 0.025). (B) Graph of the analgesia responder rate for predefined response rates in the range between 0% and 100%. ΔVAS, delta visual analogue scale; *Significant change in the pain score between tapentadol and placebo.