Table 1.
Characteristics of animal experimental groups (Zucker rats, Sprague Dawley-DIO rats, and C57BL/6J-DIO mice).
| Zucker rats | DIO rats | DIO mice | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Lean | Ob AL | Ob ER | Ob EX | Ob EREX | Lean | DIO | Lean | DIO | CR | |
| n | 10 | 10 | 10 | 10 | 10 | 12 | 14 | 4 | 8 | 8 |
| Age (weeks) | 20 | 20 | 20 | 20 | 20 | 16 | 16 | 38 | 38 | 38 |
| Body weight (kg) | 428.4 ± 20.2 | 617.7 ± 46.3a | 462.2 ± 38.5b | 606.3 ± 44.8a,c | 455.3 ± 37.6b,d | 228.5 ± 12.0 | 243.5 ± 21.5a | 34.5 ± 2.7 | 53.0 ± 2.7a,c | 42.5 ± 5.2a,b |
| Fat mass (g) | 36.7 ± 7.4 | 252.2 ± 24.8a | 184.5 ± 26.3a,b | 245.3 ± 18.9a,c | 173.6 ± 19.1a,b,d | 15.6 ± 5.2 | 32.5 ± 5.7a | – | – | – |
| Fat-free mass (g) | 321.2 ± 13.6 | 296.5 ± 17.7 | 241.1 ± 12.0a,b | 292.9 ± 21.6c | 246.0 ± 18.5a,b,d | 172.3 ± 7.8 | 170.0 ± 16.1 | – | – | – |
Ob AL obese ad libitum, Ob ER obese energy restriction, Ob EX obese exercise, Ob EREX obese energy restriction and exercise, DIO diet-induced obesity, CR caloric restriction.
aStatistically significant differences compared with lean.
bStatistically significant differences compared with Ob AL or DIO.
cStatistically significant differences compared with Ob ER or CR.
dStatistically significant differences compared with Ob EX.