Table 1:
Baseline Characteristics among Middle-old and Oldest-old patients Hospitalized with myocardial infarction
| Clinical Characteristics | Middle-old (75–84 yrs) (N=2210) Mean (SD) or N(%) |
Oldest-old (≥85 yrs) (N=831) Mean (SD) or N(%) |
p value |
|---|---|---|---|
| Demographics | |||
| Female Sex | 928 (42.0%) | 418 (50.3%) | <0.001 |
| Age (years), mean, SD | 79.2 (2.8) | 88.3 (3.0) | <0.001 |
| Nonwhite Race | 252 (11.4%) | 73 (8.8%) | 0.04 |
| Married/living as married or with partner | 1234 (55.8%) | 294 (35.4%) | <0.001 |
| Annual household income | <0.001 | ||
| <$10,000 | 111 (5.0%) | 42 (5.1%) | |
| $10,000–$29,999 | 590 (26.7%) | 238 (28.6%) | |
| $30,000–$49,999 | 404 (18.3%) | 133 (16.0%) | |
| $50,000–$69,999 | 246 (11.1%) | 66 (7.9%) | |
| $70,000–$99,999 | 166 (7.5%) | 40 (4.8%) | |
| ≥ $100,000 | 165 (7.5%) | 58 (7.0%) | |
| Refused | 313 (14.2%) | 140 (16.8%) | |
| Don't know | 215 (9.7%) | 114 (13.7%) | |
| Education Level | 0.22 | ||
| Less than high school | 277 (12.5%) | 116 (14.0%) | |
| High school | 963 (43.6%) | 367 (44.2%) | |
| 2-year or 4-year college degree | 640 (29.0%) | 217 (26.1%) | |
| Graduate or post-graduate degree | 315 (14.3%) | 120 (14.4%) | |
| Did not answer | 15 (0.7%) | 11 (1.3%) | |
| Medical History | |||
| Hypertension | 1894 (85.7%) | 701 (84.4%) | 0.35 |
| Dyslipidemia | 1408 (63.7%) | 511 (61.5%) | 0.26 |
| Tobacco use: current or ever Smoker | 1304 (59.0%) | 389 (46.8%) | <0.001 |
| Coronary artery disease | 1190 (53.8%) | 433 (52.1%) | 0.39 |
| Myocardial infarction | 612 (27.7%) | 217 (26.1%) | 0.38 |
| Atrial fibrillation | 349 (15.8%) | 206 (24.8%) | <0.001 |
| Heart failure | 400 (18.1%) | 172 (20.7%) | 0.10 |
| Peripheral vascular disease | 262 (11.9%) | 104 (12.5%) | 0.62 |
| Stroke | 234 (10.6%) | 100 (12.0%) | 0.52 |
| Diabetes mellitus | 887 (40.1%) | 241 (29.0%) | <0.001 |
| Chronic obstructive lung disease | 333 (15.1%) | 101 (12.2%) | 0.04 |
| Chronic kidney disease | 1243 (56.2%) | 588 (70.8%) | <0.001 |
| Percutaneous coronary intervention | 697 (31.5%) | 234 (28.2%) | 0.07 |
| Presentation Characteristics | |||
| ST-segment elevation myocardial infarction | 574 (26.0%) | 223 (26.8%) | 0.63 |
| Any symptom of chest pain | 1702 (77.0%) | 604 (72.7%) | 0.01 |
| Chest pain as primary symptom | 1276 (57.7%) | 438 (52.7%) | 0.01 |
| Any symptom of other discomfort | 1246 (56.4%) | 413 (49.7%) | 0.001 |
| Any other discomfort as primary symptom | 246 (11.1%) | 95 (11.4%) | 0.81 |
| Any respiratory symptom | 1076 (48.7%) | 372 (44.8%) | 0.05 |
| Respiratory as primary symptom | 284 (12.9%) | 106 (12.8%) | 0.94 |
| Any gastrointestinal symptom | 866 (39.2%) | 305 (36.7%) | 0.21 |
| Gastrointestinal as primary symptom | 140 (6.3%) | 61 (7.3%) | 0.32 |
| Any symptom of weakness | 608 (27.5%) | 233 (28.0%) | 0.77 |
| Weakness as primary symptom | 65 (2.9%) | 30 (3.6%) | 0.34 |
| Any symptom at presentation | 2145 (97.1%) | 799 (96.1%) | 0.31 |
| Hemoglobin (mg/dL) | 12..9 (2.09) | 12.5 (2.0) | <0.001 |
| Body mass index (kg/m2) | 28.1 (5.5) | 25.9 (4.67) | <0.001 |
| Decompensated heart failure | 278 (12.6%) | 120 (14.4%) | 0.18 |
| Killip class III/IV | 108 (4.9%) | 39 (4.7%) | 0.82 |
| First systolic blood pressure, mmHg | 145.7 (30.9) | 145.8 (30.8) | 0.91 |
| First diastolic blood pressure, mmHg | 78.4 (17.7) | 77.0 (17.6) | 0.06 |
| First heart rate, beats per minute | 83.7 (23.4) | 83.5 (20.6) | 0.81 |
| Glomerular filtration rate | 56.1 (20.4) | 50.1 (18.3) | <0.001 |
| Troponin >3 times upper limit of normal | 1994 (90.2%) | 773 (93.0%) | 0.02 |
| Cardiogenic shock | 42 (1.9%) | 8 (1.0%) | 0.07 |