Table 3:
Treatments and Complications Among Middle-Old and Oldest-Old Patients with myocardial infarction in Strata defined by Mobility Impairment*
| Mobility-impaired | Not mobility-impaired | |||||
|---|---|---|---|---|---|---|
| Patient Presentation Characteristics | Middle-old (N=672) N(%) |
Oldest-old (N=392) N(%) |
p value | Middle-old (N=1184) N(%) |
Oldest-old (N=309) N(%) |
p value |
| Medical Therapies on Admission | ||||||
| Aspirin | 489 (72.8%) | 265 (67.6%) | 0.06 | 883 (74.6%) | 229 (74.1%) | 1.0 |
| Theinopyridines | 376 (56.0%) | 227 (57.9%) | 0.53 | 786 (66.4%) | 206 (66.7%) | 0.93 |
| Anticoagulant use (intravenous or subcutaneous) | 535 (79.6%) | 294 (75.0%) | 0.08 | 1026 (86.7%) | 263 (85.1%) | 0.48 |
| Statin | 431 (64.1%) | 187 (47.7%) | <0.001 | 626 (52.9%) | 165 (53.4%) | 0.78 |
| Beta-blockers | 390 (58.0%) | 207 (52.8%) | 0.10 | 574 (48.5%) | 145 (46.9%) | 0.71 |
| Angiotensinogen-converting enzyme inhibitors/angiotensin-receptor blockers | 358 (53.3%) | 170 (43.4%) | <0.01 | 571 (48.2%) | 132 (42.7%) | 0.09 |
| Interventions | ||||||
| Coronary angiography | 552 (82.1%) | 255 (65.1%) | <0.001 | 1094 (92.4%) | 254 (82.2%) | <0.001 |
| PCI | 307 (45.7%) | 176 (44.9%) | 0.80 | 780 (65.9%) | 199 (64.4%) | 0.63 |
| CABG | 127 (18.9%) | 26 (6.6%) | <0.0001 | 131 (11.1%) | 16 (5.2%) | <0.01 |
| Revascularization (PCI or CABG) | 428 (63.7%) | 197 (50.3%) | <0.0001 | 902 (76.2%) | 211 (68.3%) | <0.01 |
| In-hospital outcomes | ||||||
| Major bleeding event | 85 (12.6%) | 37 (9.4%) | 0.11 | 98 (8.3%) | 7 (2.3%) | <0.001 |
| Acute kidney injury | 221 (32.9%) | 119 (30.4%) | 0.39 | 208 (17.6%) | 39 (12.6%) | 0.04 |
| Discharge to home | 394 (58.6%) | 186 (47.4%) | <0.001 | 1105 (93.3%) | 280 (90.6%) | 0.10 |
*
Mobility impairment - TUG >25 seconds or unable to complete
PCI- percutaneous coronary intervention, CABG- coronary artery bypass grafting