TABLE 2.
Tumor and sentinel node characteristics
| CLND (90) | Active surveillance (145) | P value | |
|---|---|---|---|
| Tumor characteristics | |||
| Breslow depth | |||
| Mean (IQR) | 3.46 (1.5–4.3) | 3.32 (1.5–3.9) | .736 |
| Primary site, n (%) | .002 | ||
| Upper extremity | 15 (17%) | 26 (18%) | |
| Lower extremity | 12 (13%) | 43 (30%) | |
| Trunk | 37 (41%) | 58 (40%) | |
| Head and neck | 26 (29%) | 18 (12%) | |
| Ulceration, n (%) | |||
| Present | 33 (37%) | 55 (38%) | .890 |
| Sentinel node characteristics | |||
| Number of positive sentinel lymph nodes, n (%) | .081 | ||
| 1 node | 55 (61%) | 107 (74%) | |
| 2 nodes | 25 (28%) | 30 (21%) | |
| 3 nodes | 5 (6%) | 6 (4%) | |
| >3 nodes | 5 (6%) | 2 (1%) | |
| Diameter of largest sentinel lymph node metastasis (mm), n (%) | <.001 | ||
| <0.1 mm | 3 (3%) | 28 (19%) | |
| 0.1–1 mm | 37 (41%) | 65 (45%) | |
| >1 mm | 50 (56%) | 52 (36%) | |
| Mean (IQR) | 3.49 (0.4–5.0) | 2.03 (0.1–2.0) | .011 |
Abbreviations: CLND, completion lymph node dissection; IQR, interquartile range.