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. 2020 May 28;28(1):159–166. doi: 10.1245/s10434-020-08653-w

Table 2.

Odds ratios, with 95% confidence intervals, of age in relation to mortality outcomes after esophagectomy for esophageal cancer

Deaths [N (%)] Unadjusted OR (95% CI) Adjusted OR (95% CI)
90-day all-cause mortalitya
 Age, linear 195 (11) 1.05 (1.02–1.07) 1.05 (1.02–1.07)b
 Age, years
  < 70 113 (10) 1.00 (reference) 1.00 (reference)b
  70–74 37 (11) 1.15 (0.72–1.83) 1.19 (0.72–1.96)b
  ≥ 75 45 (19) 2.63 (1.60–4.31) 2.85 (1.68–4.84)b
5-year all-cause mortalityc
 Age, linear 1299 (75) 1.02 (1.01-1.03) 1.02 (1.01–1.03)b
 Age, years
  < 70 849 (73) 1.00 (reference) 1.00 (reference)b
  70–74 251 (74) 1.02 (0.86–1.21) 1.05 (0.88–1.26)b
  ≥ 75 199 (84) 1.49 (1.22–1.81) 1.56 (1.27–1.92)b
5-year disease-specific mortalityd
 Age, linear 1004 (65) 1.01 (1.00–1.02) 1.01 (1.01–1.02)e
 Age, years
   < 70 673 (64) 1.00 (reference) 1.00 (reference)e
  70–74 193 (64) 0.98 (0.81–1.19) 1.06 (0.87–1.30)e
  ≥ 75 138 (72) 1.28 (1.02–1.61) 1.38 (1.09–1.76)e

OR odds ratio, CI confidence interval

aLinear function of survival time

bAdjusted for sex, education, Charlson comorbidity index, tumor histology, pathological tumor stage, and resection margin status

cSpline function of time after surgery with 3 knots

dSpline function of time after surgery with 4 knots

eAdjusted for sex, education, neoadjuvant therapy, tumor histology, pathological tumor stage, and resection margin status