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. 2020 Dec 8;11:585203. doi: 10.3389/fgene.2020.585203

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Copyright © 2020 Rao, Mao, Xia, Zhang, Hu, Yuan, Yang, Yan, Deng, Cai, Mao, Li and Liao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression level of host genes in A549 cells verified using RT-qPCR. (A–K) The relative expression level of each mRNA transcript was represented as the n-fold change relative to NC (0 hpi). EIF2α and ATF4 were verified in PERK-mediated unfolded protein response; IL1A, IL6, TNFAIP3, NFκB2, and GKN2 were verified in inflammatory responses; ANXA9, CLDN7, and ICAM1 were verified in cell migration; and BCL2L15 were verified in apoptosis. All data are presented as mean ± SD (n = 3 in each time point). (L) The correlation of expression level between GeneChip™ microarray and RT-qPCR was high and significant (Pearson's r = 0.93; P < 0.0001).