Fig. 4.

Knockdown of JUP promotes Gastric cancer cell migration and invasion. (A, B) Knockdown efficiencies of JUP by shJUP in NUGC-3 and MGC-803 were detected by qRT-PCR (A) and Western blot (B) (**P < 0.01 vs control shNC). GAPDH is a loading control. (C, D) Growth curves of NUGC-3 (C) and MGC-803 (D) with shJUP or shNC were performed with CCK-8 assay for 5 days. (E, F) The cell mobility and invasion potentials were tested by Wound healing assay (E) and Transwell assay (F) (*P < 0.05, **P < 0.01 vs control shRNA).