TABLE 1.
Clinical trials of registered cell therapy against COVID‐19
| Study | Registry identifier | Title | Interventions |
|---|---|---|---|
| 1 | NCT04339660 | Clinical research of human mesenchymal stem cells in the treatment of COVID‐19 pneumonia | Biological: UC‐MSCs |
| 2 | NCT04324996 |
A Phase I/II study of universal off‐the‐shelf NKG2D‐ACE2 CAR‐NK cells for therapy of COVID‐19 |
Biological: NK cells, IL15‐NK cells, NKG2D CAR‐NK cells, ACE2 CAR‐NK cells, NKG2D‐ACE2 CAR‐NK cells |
| 3 | NCT04338347 | CAP‐1002 in severe COVID‐19 disease | Biological: CAP‐1002 allogeneic cardiosphere‐derived cells |
| 4 | NCT04336254 | Safety and efficacy study of allogeneic human dental pulp mesenchymal stem cells to treat severe COVID‐19 patients | Biological: Allogeneic human dental pulp stem cells (BSH BTC & Utooth BTC) |
| 5 | NCT04315987 |
NestCell® mesenchymal stem cell to treat patients with severe COVID‐19 pneumonia |
Biological: NestCell® |
| 6 | NCT04313322 | Treatment of COVID‐19 patients using Wharton's Jelly‐Mesenchymal stem cells | Biological: WJ‐MSCs |
| 7 | NCT04288102 | Treatment with human umbilical cord‐derived mesenchymal stem cells for severe corona virus disease 2019 | Biological: MSCs |
| 8 | NCT04302519 | Novel coronavirus induced severe pneumonia treated by dental pulp mesenchymal stem cells | Biological: Dental pulp mesenchymal stem cells |
| 9 | NCT04331613 | Safety and efficacy of CAStem for severe COVID‐19 associated with/without ARDS |
Biological: CAStem |
| 10 | NCT04252118 | Mesenchymal stem cell treatment for pneumonia patients infected with 2019 novel coronavirus | Biological: MSCs |
| 11 | NCT04273646 | Study of human umbilical cord mesenchymal stem cells in the treatment of severe COVID‐19 | Biological: UC‐MSCs |
| 12 | NCT04333368 | Cell therapy using umbilical cord‐derived mesenchymal stromal cells in SARS‐CoV‐2‐related ARDS | Biological: Umbilical cord Wharton's jelly‐derived human |
| 13 | NCT04269525 | Umbilical cord (UC)‐derived mesenchymal stem cells (MSCs) treatment for the 2019‐novel coronavirus(nCOV) pneumonia | Biological: UC‐MSCs |
| 14 | NCT04299152 | Stem cell educator therapy treat the viral inflammation in COVID‐19 | Combination product: Stem cell educator‐treated mononuclear cells apheresis |
| 15 | NCT04280224 | NK cells treatment for novel coronavirus pneumonia | Biological: NK Cells |