Table 6.
Comparison of the mean value of cardiorespiratory variables in our sample of COVID‐19 patients with the pooled value calculated in acute respiratory distress syndrome patients from the literature
| Studies on ARDS from the literature, n | ARDS subjects, n | Pooled mean of ARDS patients from the literature | Confidence interval | COVID‐19 patients (n = 21) | P‐value | |
|---|---|---|---|---|---|---|
| PaO2/FiO2, mmHg | 43 | 1568 | 127 | 117–138 | 121 ± 47 | 0.560 |
| Qs/Qt | 35 | 1147 | 0.36 | 0.33–0.39 | 0.37 ± 0.11 | 0.815 |
| Static lung compliance, mL/cmH2O | 21 | 528 | 34 | 31–37 | 32 ± 12 | 0.691 |
| PEEP, cmH2O | 33 | 1389 | 10.2 | 9.3–11.2 | 11.1 ± 4.0 | 0.330 |
| Mean PAP, mmHg | 66 | 1832 | 31 | 30–32 | 27 ± 8 | 0.071 |
| PAWP, mmHg | 46 | 1580 | 13 | 12–13 | 16 ± 6 | 0.024 |
| CO, L/min | 16 | 261 | 6.9 | 6.3–7.5 | 7.3 ± 2.3 | 0.411 |
| CI, L/min/m2 | 43 | 1362 | 4.3 | 4.1–4.4 | 3.7 ± 1.1 | 0.024 |
| PVR, WU | 38 | 586 | 2.9 | 2.6–3.2 | 1.7 ± 0.8 | <0.001 |
| PVRI, mmHg/L/min/m2 | 34 | 1351 | 4.6 | 4.1–5.0 | 3.4 ± 1.6 | 0.002 |
| SVR, WU | 18 | 231 | 9.9 | 8.8–11.0 | 11.2 ± 4.3 | 0.182 |
| SVRI, mmHg/L/min/m2 | 17 | 1043 | 17.1 | 15.6–18.6 | 21.9 ± 8.2 | 0.013 |
ARDS, acute respiratory distress syndrome; CI, cardiac index; CO, cardiac output; FiO2, inspired oxygen fraction; PaO2, arterial partial pressure of oxygen; PAP, pulmonary artery pressure; PAWP, pulmonary artery wedge pressure; PEEP, positive end‐expiratory pressure; PVR, pulmonary vascular resistance; PVRI, pulmonary vascular resistance index; Qs/Qt, intrapulmonary shunt; SVR, systemic vascular resistance; SVRI, systemic vascular resistance index.