Table 3.
Levels and proportions of urinary biomarkers at ICU admission in different acute kidney injury (AKI) stages defined by combined KDIGO criteria. N = 52
| No AKI | KDIGO 1 | KDIGO 2 | KDIGO 3 | |
|---|---|---|---|---|
| N | 6 | 9 | 27 | 10 |
| U‐Albumin (mg/mmol) | 15 ± 19 | 41 ± 66 | 10 ± 12 | 16 ± 13 |
| Microalbuminuria (%) | 50 | 78 | 70 | 90 |
| Severe albuminuria (%) | 33 | 33 | 7 | 20 |
| U‐Cystatin‐CCorr (mg/mmol)†† | 0.3 ± 0.3 | 0.2 ± 0.1** | 0.1 ± 0.1** | 0.4 ± 0.4 |
| U‐Cystatin C (mg/L) | 0.9 ± 0.7 | 1.2 ± 0.8 | 0.8 ± 0.6 | 1.6 ± 0.9 |
| U‐Cystatin‐C > 0.414 mg/L (%) | 83 | 89 | 63 | 90 |
| U‐NGAL (ng/mL) | 169 ± 221 | 95 ± 79 | 73 ± 140 | 239 ± 362 |
| U‐NGALCorr (ng/mmol) | 45 ± 82 | 27 ± 37 | 10 ± 24 | 60 ± 99 |
| U‐NGAL > 100 ng/mL (%) | 33 | 33 | 11 | 50 |
| U‐KIM‐1 (ng/mL) | 2.3 ± 3.3 | 3.2 ± 2.8 | 4.5 ± 3.8 | 3.5 ± 2.5 |
| U‐KIM‐1Corr (ng/mg) | 2.5 ± 2.3 | 5.1 ± 3.8 | 5.3 ± 6.2 | 4.1 ± 2.6 |
| U‐KIM‐1 > 2.37 ng/mg (%) | 33 | 67 | 70 | 80 |
| U‐TIMP2 (ng/mL) | 6 ± 3 | 16 ± 29 | 9 ± 6 | 12 ± 9 |
| U‐TIMP2Corr (ng/mg) | 10 ± 5 | 45 ± 99 | 10 ± 6 | 14 ± 9 |
| U‐TIMP2 > 7.58 ng/mL (%) | 20 | 20 | 64 | 56 |
Abbreviations: NGAL: Neutrophil Gelatinase‐Associated Lipocalin, KIM‐1, Kidney Injury Molecule 1, TIMP‐2 Plasma Tissue Inhibitor of MetalloProteinase 2.
Indicates difference between all groups (†† P < .01).
Indicates difference between groups (**P < .01).